REINNERVATION OF VASTUS LATERALIS IS INCREASED SIGNIFICANTLY IN SENIORS (70-YEARS OLD) WITH A LIFELONG HISTORY OF HIGH-LEVEL EXERCISE

Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise

It has long been recognized that histological changes observed in aging muscle suggest that denervation contributes to muscle deterioration and that disuse accelerates the process while running activity, sustained for decades, protects against age-related loss of motor units.Here we show at the histological level that lifelong increased physical ac

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mediation: R Package for Causal Mediation Analysis

In this paper, we describe the R package mediation for conducting causal mediation analysis in applied empirical research.In many scientific disciplines, the goal of researchers is 2334-080 not only estimating causal effects of a treatment but also understanding the process in which the treatment causally affects the outcome.Causal mediation analys

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The Landscape of Noncoding RNA in Pulmonary Hypertension

The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.The majority of RNAs in the noncoding transcriptome are long noncoding RNAs (lncRNAs) with less circular RNAs (circRNAs), which are two characteristics gaining increasing attention in the forefront o

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